HALO ablation therapy (HALO) uses heat to eliminate diseased tissue known as Barrett's esophagus. By targeting only Barrett's tissue, this minimally invasive procedure leaves healthy tissue undamaged. In patients with gastroesophageal reflux disease (GERD), stomach acid and enzymes can injure the esophageal lining. Over time, this damage can cause inflammation and genetic changes to esophageal cells, causing them to become intestinal tissue. This disorder is called "intestinal metaplasia" or Barrett's esophagus.